Fluid dynamics which is one of fundamental theories of mechanical engineering can be extensively utilized in engineering processes for biological applications. Based on our strengths of mechanical technology, we are studying on bionic application such as medical diagnostics and nature-inspired design.
Stroke and hemodynamics
The cerebrovascular networks of an ischemic stroke patient, imaged using magnetic resonance angiography (MRA) at Kyung Hee University Hospital, were reconstructed to perform computational fluid dynamics (CFD) simulations. A region of interest (ROI), including the stenotic portion of the left MCA, was selected. The ROI consists of ICA, ACA, and MCA.
Hemodynamic indices such as wall shear stress and oscillatory shear index (OSI) were computed for quantitative hemodynamic analysis. Through meticulous analysis, we highlighted the predominant role of stenosis severity in cerebrovascular hemodynamics by initiating recirculating or reverse flows in the post-stenosis region.
Additionally, the flow fields in carotid arteries were also visualized using particle image velocimetry (PIV). We aim to figure out relations between the arterial shapes and vascular diseases.